Exemestane β-Spirooxirane


Product Details

CAT No.# CS-O-14934
Category Impurities
CAS 152764-31-3
Purity: >98%
Synonyms: (2'R,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione;6 Beta Epoxy Exemestane.
Application Notes: 6ß-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione is a metabolite of exemestane. Exemestane is an antineoplastic (hormonal).
References: Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)
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The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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6. Icatibant impurity 1
8. 0.1% TFA in Water ULC-MS
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16. 2-Phenoxymethanesulfonanilide
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