5-epi Emtricitabine Carboxylic Acid

IMPURITIES

Product Details

CAT No.# CS-O-15257
Category Impurities
CAS NA
Molecular Weight 261.23
Molecular Formula C8H8FN3O4S
Purity: >98%
Synonyms: (2R,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid.
Application Notes: 5-epi Emtricitabine Carboxylic Acid is an impurity of 5-epi Emtricitabine (E524980); an epimer of Emtricitabine which is a nucleoside reverse transcriptase inhibitor approved for treatment of HIV-1. Emtricitabine also has antagonistic activity against the hepatitis B virus.
References: Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Lim, S. et al.: Arch. Intern. Med., 166, 49 (2006); Smith, K., et al.: AIDS, 23, 1547 (2009)
COA / MSDS:    View COA    MSDS    Enquire
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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6. Icatibant impurity 1
7. BISPHENOL AF (RING-13C12)
8. 0.1% TFA in Water ULC-MS
9. Metamizole EP Impurity C HCl
10. Silodosin Metabolite D4
11. Brivaracetam Carboxylic acid metabolite [UCB 42145]
12. Terbuthylazine D5
13. tibolone (848)
14. (Z)-Dimethylvinphos
15. Silodosin Metabolite
16. 2-Phenoxymethanesulfonanilide
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18. Acetone HPLC
19. Nandrolone Decanoate EP impurity F
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