Ivosidenib

INHIBITORS

   
Ivosidenib is a Inhibitors of Ivosidenib with CAS Registry No: 1448347-49-6
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CAT No. CS-O-16987
Category Inhibitors
Parent API Ivosidenib
CAS 1448347-49-6
Mol. Weight 582.97 g/mol
Mol. Formula C28H22ClF3N6O3
View COA View MSDS
More info about Ivosidenib
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Synonyms 1448346-63-1; Ivosidenib, AG-120; AG120; AG 120; RG-120; RG 120; RG120; (S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
Purity (%) >98
References Caino MC, Altieri DC. Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy. Clin Cancer Res. 2016 Feb 1;22(3):540-5. doi: 10.1158/1078-0432.CCR-15-0460. Review. PubMed PMID: 26660517; PubMed Central PMCID: PMC4738153. Chen J, Yang J, Cao P. The Evolving Landscape in the Development of Isocitrate Dehydrogenase Mutant Inhibitors. Mini Rev Med Chem. 2016;16(16):1344-1358. PubMed PMID: 27292784.
Smiles O=C([C@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@H](C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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