Product Detail
(1S,2R) Bortezomib
Bortezomib Chiral
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Chiral
API Family
Bortezomib
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
(1S,2R) Bortezomib Product Information
(1S,2R) Bortezomib is listed under Chiral. It is associated with Bortezomib and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-20087.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
(1S,2R) Bortezomib
CAS No.
1132709-16-0
CAT No.
CS-O-20087
Molecular Formula
C19H25BN4O4
Molecular Weight
384.2
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
OB([C@@H](CC(C)C)NC([C@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O)O
IUPAC Name
((S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
Purity by HPLC
Not less than 95 %
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"(1S,3R)-Bortezomib is an diastereomer of Bortezomib , the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus"
Synonyms
Bortezomib Impurity (R,S-Isomer)
Application Notes
"(1S,3R)-Bortezomib is an diastereomer of Bortezomib , the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus"
References
"Nawrcki, S,T,, et al:cacer Reseach, 65, 11510 (2005); Drahlc,:chem, and Eng, News, 87, 41 (2009)"
Related Bortezomib Products
N-(1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Hydroxy Bortezomib
N-(Boc-L-phenylalanyl)isopentylamine
Bortezomib Impurity 29
Bortezomib Impurity 10
![Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0.2.6]dec-4-yl)-butylcarbamoyl]-2-phenyl-ethyl)-amide chemical structure](https://structures.clearsynth.com/CS-O-42129.png)
Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0.2.6]dec-4-yl)-butylcarbamoyl]-2-phenyl-ethyl)-amide
Bortezomib Impurity 11
Bortezomib Amino R Isomer (TFA salt)
![N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide chemical structure](https://structures.clearsynth.com/CS-T-032551.PNG)
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
