(1S,2R) Bortezomib
IMPURITIES    
Availability: In-Stock
Dispatch to United States by: 30-Jan-2020 5:00 PM
CAT No. CS-O-20087
Category Impurities
Parent API Bortezomib
CAS 1132709-16-0
Mol. Weight 384.24 g/mol
Mol. Formula C₁₉H₂₅BN₄O₄
View COA View MSDS
Product Description
Stock Status In-Stock
Dispatch to United States by: 30-Jan-2020 5:00 PM
Synonyms Not available
Storage Conditions Store at refrigerator (2-8°C) for long term storage
Purity (%) Not less than 95 %
Solubility Soluble in chloroform
Appearance Off white to pale yellow solid
Application Notes "(1S,3R)-Bortezomib is an diastereomer of Bortezomib , the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus"
References "Nawrcki, S,T,, et al:cacer Reseach, 65, 11510 (2005); Drahlc,:chem, and Eng, News, 87, 41 (2009)"
Pubchem Id 93860
Smiles B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Bortezomib
- Stable Isotopes of Bortezomib
- Metabolites of Bortezomib
- Impurities of Bortezomib
- Glucuronides of Bortezomib
- Intermediates of Bortezomib

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