Tacrolimus
API STANDARDS    
Availability: In-Stock
Dispatch to United States by: 23-Jan-2020 5:00 PM

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CAT No. CS-O-30787
Category API Standards
Parent API Tacrolimus
CAS 104987-11-3
Mol. Weight 804.02 g/mol
Mol. Formula C44H69NO12
View COA View MSDS
Product Description
Stock Status In-Stock
Dispatch to United States by: 23-Jan-2020 5:00 PM
Synonyms Fujolide, Advagraf, 15,19-Epoxy-3H-pyrido(2lotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-
Purity (%) >98%
Application Notes A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
References Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318,|???|???????
Smiles CO[[email protected]@H]1[[email protected]]([[email protected]](C[[email protected]](C/C(C)=C\[[email protected]](C(C[[email protected]](O)[[email protected]]2C)=O)CC=C)C)OC)([H])O[[email protected]@](O)(C(C(N(CCCC3)[[email protected]]3([H])C(O[[email protected]@H]2/C(C)=C/[[email protected]](CC[[email protected]]4O)C[[email protected]]4OC)=O)=O)=O)[[email protected]](C)C1
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Tacrolimus
- Stable Isotopes of Tacrolimus
- Metabolites of Tacrolimus
- Impurities of Tacrolimus
- Glucuronides of Tacrolimus
- Intermediates of Tacrolimus

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