Fidaxomicin
API STANDARDS    
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CAT No. CS-O-30824
Category API Standards
Parent API Fidaxomicin
CAS 873857-62-6
Mol. Weight 1058.04 g/mol
Mol. Formula C52H74Cl2O18
View COA View MSDS
Product Description
Stock Status In-Stock
Dispatch to US by: 8-Jul-2020 5:00 PM
Synonyms (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5yl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxymethyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxccloctadca-3,5,9,13,15-pentaen-2-one;clostomcin B1; Difcid; Difclir; Fidaxomcin; Fidaxomcin; Lipiarmcin; Lipiarmcin; Lipiarmcin A 3; OPT 80; PAR 01; PAR 101; R-Ticumcin B; Ticumcin B
Storage Conditions -20° C
Purity (%) >98%
Solubility DMSO, Methanol
Appearance White Solid
Application Notes Fidaxomicin is a nonabsorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen.
References Babakhani, F., et al.:clin. Infct. Dis., 55, S162 (2012); Venugopal, A., et al.:clin. Infct. Dis., 54, 568 (2012)
Smiles O=C(C(C(O)=C(Cl)C(O)=C1Cl)=C1CC)O[C@H]([C@H](O[C@H]2OC/C(C(O[C@](C/C=C3C)([H])[C@H](O)C)=O)=C\C=C\C[C@](/C(C)=C\[C@H](CC)[C@@H](O[C@@](OC(C)(C)[C@@H](OC(C(C)C)=O)[C@@H]4O)([H])[C@H]4O)\C(C)=C/3)([H])O)C)[C@@H]([C@@H]2OC)O
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Fidaxomicin
- Stable Isotopes of Fidaxomicin
- Metabolites of Fidaxomicin
- Impurities of Fidaxomicin
- Glucuronides of Fidaxomicin
- Intermediates of Fidaxomicin


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