Temsirolimus Impurity 1

IMPURITIES

CAT No.# CS-P-02150
Category Impurities
CAS 408321-08-4
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Molecular Weight 1016.29
Molecular Formula C55H85NO16
Synonyms: Temsirolimus 7-O-Desmethyl Impurity; (1R,2R,4S)-2-methoxy-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,32S,35R)-1,18,30-trihydroxy-19-methoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]cyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
Application Notes: 7-O-Desmethyl Temsirolimus is an impurity of Temsirolimus which is an Ester analog of Rapamycin.
References: Raymond, E., et al.: J. Clin. Oncol., 22, 2336 (2004); Galanis, E., et al.: J. Clin. Oncol., 23, 5294 (2005)
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