Bortezomib Impurity 3
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CAT No. CS-P-07311
Category Impurities
Parent API Bortezomib
CAS 289472-80-6
Mol. Weight 270.29 g/mol
Mol. Formula C15H15N3O2
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Product Description
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Synonyms N,N-dimethyl-4-((4-nitrophenyl)diazenyl)anilin; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; CS-T-03255; 289472-80-6 (S-isomer); Bortezomib Impurity A.
Application Notes N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.
References Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);
Pubchem Id 67121778
Smiles C1=CC=C(C=C1)CC(C(=O)N)NC(=O)C2=NC=CN=C2
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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Related Results

- API Standards of Bortezomib
- Stable Isotopes of Bortezomib
- Metabolites of Bortezomib
- Impurities of Bortezomib
- Glucuronides of Bortezomib
- Intermediates of Bortezomib

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