Avelestat
API STANDARDS    
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CAT No. CS-T-04383
Category API Standards
Parent API Avelestat
CAS 848141-11-7
Mol. Weight 545.53 g/mol
Mol. Formula C25H22F3N5O4S
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Product Description
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Synonyms 1,2-dihydro-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-[[5-(methylsulfonyl)-2-pyridinyl]methyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]-3-Pyridinecarboxamide
Purity (%) >98%
Application Notes Avelstat inhibits plasma neutrophil elastase (NE) activity in zymosan-stimulated whole blood, and also inhibits NE activity on the surface of stimulated polymorphonuclear cells and in the supernatant of primed, stimulated cells.
References Stevens, T., et al.: J. Pharmacol. Exp. Ther., 339, 313 (2011)
Pubchem Id 46861623
Smiles CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Avelestat
- Stable Isotopes of Avelestat
- Metabolites of Avelestat
- Impurities of Avelestat
- Glucuronides of Avelestat
- Intermediates of Avelestat


Quality Assurance


c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c4
ISO 17034:2016
c5
ISO/IEC 17025:2017
c5
NIST Calibrated