(-)-Corey Lactone Diol


Product Details

CAT No.# CS-T-13328
Category Impurities
CAS 32233-40-2
Molecular Weight 172.18
Molecular Formula C8H12O4
Stock Status: In-Stock
Purity: >98%
Melting Point: 118-120
Solubility: DMSO, Methanol
Appearance: Beige Solid
Synonyms: (3aR,4S,5R,6aS)Hexahydro-5-hydroxy-4-(hydroxymethyl)-an-2-one;54423-47-1;Lubiprostone related compound 6.;(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
Application Notes: (-)-Corey Lactone Diol is an intermediate of Iloprost and shows inhibitory activity towards lactamase. Iloprost is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References: Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008); Scorza, R. et al.: J. Rheutamol., 24, 1944 (1997); Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (1995);
Storage: -20°C Freezer
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COA / MSDS:    View COA    MSDS
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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