Dabrafenib | CAS 1195765-45-7 | API Standards

Dabrafenib

Dabrafenib
CAT No. CS-T-14322
Category API Standards
Parent API Dabrafenib
CAS 1195765-45-7
Purity (%) >98%
Application Dabrafenib is an inhibitor of mutated BRAF kinase and has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.
References Hauschild, A., et al.: Lancet, 380, 358 (2012); Falchook, G.S., et al.: Lancet, 379, 1893 (2012); Ascierto, P.A., et al.: J. Clin. Oncol., 31, 3205 (2013)
Mol. Weight 519.56 g/mol
Formula C23H20F3N5O2S2
Stock Status For Exact delivery date, please contact sales@clearsynth.com
Synonyms N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide;N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide.
Documents COA   MSDS

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