(-)-N-Deacetyl Colchicine


Product Details

CAT No.# CS-T-14488
Category Impurities
CAS 3476-50-4
Molecular Weight 357.4
Molecular Formula C20H23NO5
Stock Status: In-Stock
Purity: >98%
Melting Point: 80-85
Solubility: Chloroform, Dichlormethane, DMSO, Methanol
Appearance: Yellow Solid
Synonyms: (10S)-10-amino-3,4,5,14- tetramethoxy2,4,6,11,14-hexaen-13-one
Application Notes: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
References: Sharma, S., et al.: Biochem., 49, 2932 (2010), Bartusik, D., et al.: Bioorg. Chem., 38, 1 (2010), Passarella, D., et al.: Eur. J. Med. Chem., 45, 219 (2010),
Storage: -20°C Freezer, Under Inert Atmosphere
Shipping: Free Shipping for worldwide on order above 2000 USD , Extra charges for Dry ice shipment 80$*
COA / MSDS:    View COA    MSDS
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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