Dorsomorphin Dihydrochloride
Availability: Available - Dispatch by : 25-Dec-2019 5:00 PM
CAT No. CS-T-21334
Category API Standards
Parent API Dorsomorphin
CAS 1219168-18-9
Mol. Weight 472.41 g/mol
Mol. Formula C24H27Cl2N5O
View COA View MSDS
Product Description
Stock Status Available - Dispatch by : 25-Dec-2019 5:00 PM
Synonyms 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine Dihydrochloride
Purity (%) >98%
Application Notes Dorsomorphin is an AMP-activated kinase (AMPK) inhibitor. Dorsomorphin selectively inhibits the bone morphogenetic protein (BMP) type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation, target gene transcription and osteogenic differentiation. Dorsomorphin has shown to to increase cisplatin-induced apoptosis, which was associated with hyper-induction of the tumor suppressor p53.
References Shen, Q.W., Gerrard, D.E., Du, M.: Meat Sci., 78, 323 (2008); Yu, P., et. al.: Nat. Chem. Biol., 4, 33 (2008); Kim, H., et. al.: J. Biol. Chem., 283, 3731 (2008)
Smiles C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

Have questions about this product or Require Pricing?
Let us help you.
Our automated system will send you a quote for your specific qty along with Discount, timelines or Stock status.

Stock Status   Bulk Quote   Required Pricing

Guaranteed Delivery
We ship worldwide through leading logistics partners.
Our shipment reaches you from our stock point closest to your country (US)

Related Results

- API Standards of Dorsomorphin
- Stable Isotopes of Dorsomorphin
- Metabolites of Dorsomorphin
- Impurities of Dorsomorphin
- Glucuronides of Dorsomorphin
- Intermediates of Dorsomorphin

You may be also interested

Quality Assurance

ISO 9001:2005
OHSAS 18001:2007
ISO 14001:2005
NIST Calibrated

Customer Reviews