Hydroxy Fasudil Hydrochloride

METABOLITES

Product Details

CAT No.# CS-T-27395
Category Metabolites
CAS 155558-32-0
Molecular Weight 343.83
Molecular Formula C14H18ClN3O3S
Purity: >98%
Melting Point: >250
Solubility: Aqueous Acid, Methanol (Sparingly)
Appearance: Off-White Solid
Synonyms: 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine Hydrochloride
Application Notes: A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
References: Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),
COA / MSDS:    View COA    MSDS    Enquire
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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7. Icatibant impurity 1
8. BISPHENOL AF (RING-13C12)
9. 0.1% TFA in Water ULC-MS
10. Metamizole EP Impurity C HCl
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13. Terbuthylazine D5
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This page contains information about Hydroxy Fasudil Hydrochloride Cas 155558-32-0 and its Metabolites.
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