Hydroxy Fasudil Hydrochloride
Availability: Available - Dispatch by : 25-Dec-2019 5:00 PM
CAT No. CS-T-27395
Category Metabolites
Parent API Fasudil
CAS 155558-32-0
Mol. Weight 343.83 g/mol
Mol. Formula C14H18ClN3O3S
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Product Description
Stock Status Available - Dispatch by : 25-Dec-2019 5:00 PM
Synonyms 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine Hydrochloride
Purity (%) >98%
Melting Point (℃)>250 
Solubility Aqueous Acid, Methanol (Sparingly)
Appearance Off-White Solid
Application Notes A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
References Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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Related Results

- API Standards of Fasudil
- Stable Isotopes of Fasudil
- Metabolites of Fasudil
- Impurities of Fasudil
- Glucuronides of Fasudil
- Intermediates of Fasudil

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