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For Research Purposes only. Not for Personal use.
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CAS No.
127-07-1
Product Code
CS-T-28915
M.F.
CH4N2O2
M.W.
76.1
Smiles
NC(NO)=O
Category
Intermediate
API Family
Fluorouracil
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
1-Hydroxyurea
References
"Ratcliffe, W,, et al,: Lancet, 339, 164 (1992), Roodman, G,, et al,: Cancer, 80, 1557 (1997), Horwitz, M,, et al,: J, Clin, Endocrinol, Metab,, 2003, 88, 1603 (2003), "
Synonyms
N-Carbamoylhydroxylamine
Application Notes
An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
