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CAT No. CS-T-39142
Category Inhibitors
CAS 1144035-53-9
Mol. Weight 478.33 g/mol
Mol. Formula C22H21Cl2N3O5
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Product Description
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Synonyms 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazinel Ester;3,5-dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate
Purity (%) >98%
Application Notes PF8380 is a novel autotaxin inhibitor which reduces lysophosphatidic acid levels in plasma and at the site of inflammation.
References Gierse, J., et al.: J. Pharmacol. Exp. Ther., 334, 310 (2010); Mize, C.D., et al.: J. Molec. Graph. Model., 31, 76 (2011);
Smiles O=C(N1CCN(CCC(C2=CC=C3NC(OC3=C2)=O)=O)CC1)OCC4=CC(Cl)=CC(Cl)=C4
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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