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CAT No. CS-T-42222
Category Inhibitors
CAS 606143-52-6
Mol. Weight 457.68 g/mol
Mol. Formula C17H15BrClFN4O3
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Product Description
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Synonyms 5-[(4-Bromo-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carbimidic acid
Purity (%) >98%
Application Notes It is a tight-binding, uncompetitive inhibitor of mitogen-activated protein kinase kinases (MEK) 1 and 2 currently in clinical development.
References Ciardiello, F., et al.: Clin. Cancer Res., 7, 1459 (2001), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001),
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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