Tariquidar
API STANDARDS    
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CAT No. CS-T-43154
Category API Standards
Parent API Tariquidar
CAS 206873-63-4
Mol. Weight 646.73 g/mol
Mol. Formula C38H38N4O6
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Product Description
Stock Status For Exact delivery date, please contact sales@clearsynth.com
Synonyms N-[2-[[[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amiquinolinecarboxamide
Storage Conditions For long term store at -20°C
Purity (%) >98%
Melting Point (℃)>204 
Solubility Chloroform, DMSO
Appearance Pale Yellow Solid
Application Notes Tariquidar is a p-glycoprotein drug efflux pump inhibitor. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both.Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer.
References Fox, E., et al.: Expert. Rev. Ainticancer. Ther., 7, 447 (2007); Hernandez, D., et al.: Biochem. Pharmacol., 85, 21 (2013); Bauer, F., et al.: Euro. J. Pharmacol., 696, 18 (2012);
Smiles COC1=CC2=C(C=C1OC)CN(CCC3=CC=C(C=C3)NC(C4=CC(OC)=C(C=C4NC(C5=CN=C6C=CC=CC6=C5)=O)OC)=O)CC2
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Tariquidar
- Stable Isotopes of Tariquidar
- Metabolites of Tariquidar
- Impurities of Tariquidar
- Glucuronides of Tariquidar
- Intermediates of Tariquidar


Quality Assurance


c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c4
ISO 17034:2016
c5
ISO/IEC 17025:2017
c5
NIST Calibrated