2,2-Dimethylthiopropionamide

FINE CHEMICALS

   
2,2-Dimethylthiopropionamide belongs to the category of Fine Chemicals with CAS Registry No: 630-22-8

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CAT No. CS-T-45663
Category Fine Chemicals
CAS 630-22-8
Mol. Weight 117.21 g/mol
Mol. Formula C5H11NS
View COA View MSDS
More info about 2,2-Dimethylthiopropionamide
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Synonyms 2,2-Dimethylpropanethioamide;2,2-dimethylpropanethioamide
Purity (%) >98%
Application Notes 2,2-Dimethylthiopropionamide is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 2,2-Dimethylthiopropionamide is also used as a reagent to prepare sulfonyl-substituted 4,5-diarylthiazoles, compounds that act as cyclooxygenase-2 inhibitors (anti-inflammatory agents).
References Carter, J., et al.: Bioorg. Med. Chem. Lett., 9, 1167 (1999); Rheault, T., et al.: ACS Med. Chem. Lett., 4, 358 (2013);
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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