2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid
IMPURITIES    
Availability: In-Stock
Dispatch by : 16-Nov-2019 5:00 PM
CAT No. CS-T-47670
Category Impurities
Parent API Febuxostat
CAS 1239233-86-3
Mol. Weight 334.39 mol/g
Mol. Formula C16H18N2O4S
Product Description
Stock Status In-Stock
Dispatch by : 16-Nov-2019 5:00 PM
Synonyms 2-yl]-4-methyl-
1,3-thiazole-5-carboxylic acid
Storage Conditions
Purity (%) >98%
Melting Point (℃)225-229 
Solubility DMSO, Methanol
Appearance White Solid
Application Notes 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid is an impurity of Febuxostat , an xanthine oxidase/xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout. ;Impurity in commercial preparations of Febuxostat
References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),
Pubchem Id 46849409
Smileys CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C(=O)N)C(=O)O
View COA View MSDS
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

Quality Assurance

c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c5
NIST Calibrated
Related Results

- API Standards of Febuxostat
- Stable Isotopes of Febuxostat
- Metabolites of Febuxostat
- Impurities of Febuxostat
- Glucuronides of Febuxostat
- Intermediates of Febuxostat

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