2'-Deoxy-5-azacytidylyl-(3'5')-2'-deoxy-guanosine Sodium Salt
Availability: This product can be dispatched by 7-Mar-2020
CAT No. CS-T-51917
Category Nucleotides
CAS 929904-85-8
Mol. Weight 579.39 g/mol
Mol. Formula C18H23N9NaO10P
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Product Description
Stock Status This product can be dispatched by 7-Mar-2020
Synonyms (2R,3R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2S,3S)-5-(2-amino-6-oxo-3H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) phosphate
Purity (%) >98%
Application Notes 2'-Deoxy-5-azacytidylyl-(3'5')-2'-deoxy-guanosine is an DNA methylation inhibitor in vivo and was shown to effectively tolerated in tumor-free mouse and was found to be similarly effective in reducing tumor growth.
References Chuang, J.C., et al.: Mole. Cancer. Therapeu., 9, 1443 (2010);
Smiles C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC(=NC5=O)N)O.[Na+]
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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