Bisindolylmaleimide X Hydrochloride
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CAT No. CS-T-67091
Category Heterocycles
CAS 145317-11-9
Mol. Weight 460.96 g/mol
Mol. Formula C26H25ClN4O2
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Product Description
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Synonyms 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Hydrochloride; 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Monohydrochloride;
Application Notes Bisindolylmaleimide X hydrochloride is a potent and selective cell-permeable protein kinase C (PKC) inhibitor. Studies reveal that inhibition of PKCa by Bisindolylmaleimide X and other similar PKC inhibitors has been associated with enhanced cardiac controler.
Smiles O=C(C(C1=C(CC(CN)CC2)N2C3=C1C=CC=C3)=C4C5=CN(C)C6=C5C=CC=C6)NC4=O.[H]Cl
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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NIST Calibrated