N-[(7R)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl ester
IMPURITIES    
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CAT No. CS-T-91200
Category Impurities
CAS 1083065-09-1
Mol. Weight 526.67 g/mol
Mol. Formula C33H38N2O4
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Product Description
Stock Status For Exact delivery date, please contact sales@clearsynth.com
Solubility Deuterated Chloroform
Appearance Colourless Oil
Application Notes N-[(7R)-6,7-Dihydro-5-[(4-methoxyphenyl)methyl]-6-oxo-5H-dibenz[b,d]azepin-7-yl]-carbamic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl ester is an impurity in the synthesis of (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one, a building block for secretase inhibitors for treatment of Alzheimer's disease. Several secretase inhibitors have been described that contain this compound.
Smiles O=C(O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1)N[C@@H]2C3=CC=CC=C3C4=CC=CC=C4N(CC5=CC=C(OC)C=C5)C2=O
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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c1
ISO 9001:2005
c4
OHSAS 18001:2007
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ISO 14001:2005
c4
ISO 17034:2016
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ISO/IEC 17025:2017
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NIST Calibrated