Nimesulide EP Impurity A
IMPURITIES    
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CAT No. CS-T-92564
Category Impurities
Parent API Nimesulide
CAS 51765-56-1
Mol. Weight 353.31 g/mol
Mol. Formula C13H11N3O7S
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Product Description
Stock Status For Exact delivery date, please contact sales@clearsynth.com
Synonyms N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide; 4?,6?-Dinitro-2?-phenoxymethanesulfonanilide
Purity (%) >98
Application Notes 4?,6?-Dinitro-2?-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)
Pubchem Id 85825034
Smiles CS(=O)(=O)NC1=C(C=C(C=C1OC2=CC=CC=C2)[N+](=O)[O-])[N+](=O)[O-]
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy


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Related Results

- API Standards of Nimesulide
- Stable Isotopes of Nimesulide
- Metabolites of Nimesulide
- Impurities of Nimesulide
- Glucuronides of Nimesulide
- Intermediates of Nimesulide


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c1
ISO 9001:2005
c4
OHSAS 18001:2007
c5
ISO 14001:2005
c4
ISO 17034:2016
c5
ISO/IEC 17025:2017
c5
NIST Calibrated