Nimesulide EP Impurity A

IMPURITIES

Product Details

CAT No.# CS-T-92564
Category Impurities
CAS 51765-56-1
Molecular Weight 353.31
Molecular Formula C13H11N3O7S
Purity: >98
Synonyms: N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide; 4�,6�-Dinitro-2�-phenoxymethanesulfonanilide
Application Notes: 4�,6�-Dinitro-2�-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production
References: Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)
COA / MSDS:    View COA    MSDS    Enquire
The balance used are calibrated with weights traceable to National Standards NIST for accuracy
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