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Dr. Reddy received his Ph.D. in Computational Chemistry from the Central University of Hyderabad and held postdoctoral fellowships at University of Texas at Austin and UNC at Chapel Hill; where he studied free energies of small- drug molecules as well as proteins which are related to discovering drugs for AIDS, Cancer and Diabetes using Bioinformatics, Cheminformatics and Computational approaches as well as Monte Carlo, molecular dynamics simulations and free energy perturbation methods. From 1989 - 1992, he was a Scientist/Senior Research Scientist at Agouron Pharmaceuticals (now Pfizer), San Diego. Dr. Reddy's Computer-Aided Drug Design (CADD) efforts using Bioinformatics, Cheminformatics and Computational Chemistry methods at Pfizer led to several clinical candidates for cancer and one FDA approved drug for AIDS (Viracept). From 1992-2009, he served at Gensia Pharmaceuticals, Inc. (now Metabasis Therapeutics, Inc.) in various capacities and finally as an Executive Director for novel drug discovery, working in the research areas of cardiovascular, pain, cancer, hyperlipidemia, and diabetes using rational drug discovery approaches, and his efforts led to several clinical and pre-clinical candidates which are being developed for Cancer, Pain, Type-2 Diabetes, AIDS & Hyperlipidemia.
Dr. Reddy's current research interests are in developing highly accurate novel CADD methods as well as use of Bioinformatics, Cheminformatics, Structural Biology and novel CADD methods for the discovery of novel drugs by saving significant amount of time and money during drug discovery process for critical human diseases such as diabetes, AIDS and cancer. Dr. M. Rami Reddy is an author of over 100 scientific publications; many of them are in prestigious Journal of American Chemical Society and Proceeding of National Academy of Sciences, USA. He holds ten patents and is an author of two text books on rational drug design. He is also an author of several novel CADD programs. Dr Reddy has extensively lectured all over the world in the field. He is currently the Section Editor for Computer Assisted Drug Design (CADD) of Current Pharmaceutical Design. He has organized seven symposiums on computational aspects of Rational Drug Design and Structure Based Drug Design at various American Chemical society National meetings.
Dr. Reddy has wide spectrum of knowledge in the field of drug discovery, and has made significant contributions in his 25-year research career. He is one of the few experts in the world in developing novel computational methods and their applications for drug discovery. He was responsible for successfully developing a highly accurate Computer-Aided Drug Design (CADD) Technology intended to speed-up drug discovery process. He is currently co-founder and chairman of RR Labs Inc and Rational Labs Inc, San Diego, CA, USA and Hyderabad, India. In addition, he is a Visiting Professor at Centre for Modeling, Simulations and Design (CMSD) at University of Hyderabad, Hyderabad and the recipient of TANA (USA) 2009 award for excellence in Science and also received a major grant from the Department of Science and Technology to further develop his Novel CADD Technology for discovering novel drugs for critical human diseases by reducing time and costs during drug discovery process.
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