Darunavir Glucuronides

Darunavir (DRV), sold under the brand name Prezista among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It is often used with low doses of ritonavir or cobicistat to increase darunavir levels. It may be used for prevention after a needlestick injury or other potential exposure. It is taken by mouth once to twice a day.

Common side effects include diarrhea, nausea, abdominal pain, headache, rash and vomiting. Severe side effects include allergic reactions, liver problems, and skin rashes such as toxic epidermal necrolysis. While poorly studied in pregnancy it appears to be safe for the baby. It is of the protease inhibitor (PI) class and works by blocking HIV protease.

Developed by pharmaceutical company Tibotec, darunavir is named after Arun K. Ghosh, the chemistry professor who discovered the molecule at the University of Illinois at Chicago. It was approved by the Food and Drug Administration (FDA) in June 2006. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.

The fixed-dose combination medication darunavir/cobicistat (Rezolsta) is available as a single pill.




Displaying 36 results last updated on 21-Nov-2022

Darunavir Glucuronides



Other Reference Standards of Darunavir


CAT No. COMPOUND CATEGORY IMAGE
CS-P-07698 D-(+)-Darunavir Darunavir Chiral D-(+)-Darunavir
CS-O-00249 Darunavir Darunavir API Standards Darunavir
CS-CX-00276 Darunavir 13C6 Darunavir Stable Isotopes Darunavir 13C6
CS-O-15899 Darunavir Amine dimer impurity Darunavir Impurities Darunavir Amine dimer impurity
CS-T-82431 Darunavir Carbamic Acid Methyl Ester Darunavir Impurities Darunavir Carbamic Acid Methyl Ester
CS-O-02984 Darunavir D9 Darunavir Stable Isotopes Darunavir D9
CS-O-12076 Darunavir Diamino impurity Darunavir Impurities Darunavir Diamino impurity
CS-O-12079 Darunavir Difuranyl impurity Darunavir Impurities Darunavir Difuranyl impurity
CS-O-00287 Darunavir Ethanolate Darunavir Fine Chemicals Darunavir Ethanolate
CS-O-12035 Darunavir furan dimer impurity Darunavir Impurities Darunavir furan dimer impurity
CS-P-04011 Darunavir Impurity 10 Darunavir Impurities Darunavir Impurity 10
CS-P-08297 Darunavir Impurity 11 Darunavir Impurities Darunavir Impurity 11
CS-P-08256 Darunavir Impurity 8 (R,R-Isomer) Darunavir Impurities Darunavir Impurity 8 (R,R-Isomer)
CS-P-07699 Darunavir Impurity A Enantiomer Darunavir Impurities Darunavir Impurity A Enantiomer
CS-EO-00628 Darunavir impurity B Darunavir Impurities Darunavir impurity B
CS-O-12078 Darunavir Isomer 1 Darunavir Impurities Darunavir Isomer 1
CS-O-12081 Darunavir Isomer 2 Darunavir Impurities Darunavir Isomer 2
CS-ED-01184 Darunavir metabolite M6 Darunavir Metabolites Darunavir metabolite M6
CS-O-12077 Darunavir Nitro complex impurity Darunavir Impurities Darunavir Nitro complex impurity
CS-O-34249 Darunavir N-methyl urea impurity Darunavir Impurities Darunavir N-methyl urea impurity
CS-O-12037 Darunavir Urea impurity Darunavir Impurities Darunavir Urea impurity
CS-O-12038 Darunavir СВZ amino impurity Darunavir Impurities Darunavir СВZ amino impurity
CS-O-12039 Darunavir СВZ furan impurity Darunavir Impurities Darunavir СВZ furan impurity
CS-O-12075 Darunavir СВZ urea impurity Darunavir Impurities Darunavir СВZ urea impurity
CS-T-27082 Hydroxy Darunavir Darunavir Intermediates Hydroxy Darunavir
CS-T-94175 N-[3S-benzyloxycarbonylamino-2R-hydroxy-4-phenyl]-N-isobutylamine Darunavir Impurities N-[3S-benzyloxycarbonylamino-2R-hydroxy-4-phenyl]-N-isobutylamine
CS-T-79114 "(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ylcarbonyl Darunavir" Darunavir Impurities
CS-P-07701 "Darunavir Impurity 7 (S,S-Isomer)" Darunavir Impurities
CS-T-74134 (1R,2S)-Darunavir Darunavir Impurities (1R,2S)-Darunavir
CS-T-73368 1-epi-Darunavir Darunavir Impurities 1-epi-Darunavir
CS-T-74016 2-epi-Darunavir Darunavir Impurities 2-epi-Darunavir
CS-T-55921 3-Hydroxy Darunavir Darunavir Intermediates 3-Hydroxy Darunavir
CS-T-55922 4-Hydroxy Darunavir Darunavir Intermediates 4-Hydroxy Darunavir


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