Losartan and its related Impurities
Impurities in Losartan can arise during the manufacturing process or storage of the drug.
Last updated on 12-Mar-2023
The most common Losartan Impurities are listed below:
PRODUCT | STRUCTURE |
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Des[2-(1H-tetrazol-5-yl)] 2-CyanolosartanDes[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan CAT No.: CS-T-16636 CAS Number: 114772-55-3 Category: Losartan Impurities Molecular Formula: C₂₂H₂₂ClN₃O |
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Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan CarboxaldehydeDes[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde CAT No.: CS-T-16638 CAS Number: 124750-67-0 Category: Losartan Impurities Molecular Formula: C₂₂H₂₀ClN₃O |
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Losartan a-Butyl-losartan Aldehyde AdductLosartan a-Butyl-losartan Aldehyde Adduct CAT No.: CS-T-57302 CAS Number: 1159977-48-6 Category: Losartan Impurities |
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Losartan Acetyloxy ImpurityLosartan Acetyloxy Impurity CAT No.: CS-O-15333 CAS Number: 253678-97-6 Category: Losartan Impurities |
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Losartan Acetyloxy N1-Trityl ImpurityLosartan Acetyloxy N1-Trityl Impurity CAT No.: CS-O-15336 CAS Number: 154709-17-8 Category: Losartan Impurities |
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Losartan AmineLosartan Amine CAT No.: CS-EO-01398 CAS Number: 141949-89-5 Category: Losartan Impurities Molecular Formula: C22H24ClN7 |
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Losartan Azide impurityLosartan Azide impurity CAT No.: CS-O-35717 CAS Number: 727718-93-6 Category: Losartan Impurities Molecular Formula: C₂₂H₂₂ClN₉ |
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Losartan Dimer AzideLosartan Dimer Azide CAT No.: CS-EO-02121 CAS Number: 2755908-51-9 Category: Losartan Impurities Molecular Formula: C44H43Cl2N15 |
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Losartan EP Impurity BLosartan EP Impurity B CAT No.: CS-O-11950 CAS Number: 160514-13-6 Category: Losartan Impurities |
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Losartan EP Impurity CLosartan EP Impurity C CAT No.: CS-K-00233 CAS Number: 114799-13-2 Category: Losartan Impurities Molecular Formula: 422.91 mol/g |
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Losartan EP Impurity FLosartan EP Impurity F CAT No.: CS-O-15329 CAS Number: 1332713-64-0 Category: Losartan Impurities |
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Losartan EP Impurity LLosartan EP Impurity L CAT No.: CS-T-57305 CAS Number: 230971-71-8 Category: Losartan Impurities Molecular Formula: C₄₄H₄₄Cl₂N₁₂O |
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Losartan EP Impurity MLosartan EP Impurity M CAT No.: CS-O-15331 CAS Number: 230971-72-9 Category: Losartan Impurities Molecular Formula: C₄₄H₄₄Cl₂N₁₂O |
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Losartan Hydroxy N1-Trityl ImpurityLosartan Hydroxy N1-Trityl Impurity CAT No.: CS-O-15337 CAS Number: 154709-18-9 Category: Losartan Impurities |
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Losartan Impurity 1Losartan Impurity 1 CAT No.: CS-EO-01623 Category: Losartan Impurities Molecular Formula: C22H21ClN6 |
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Losartan Impurity 15Losartan Impurity 15 CAT No.: CS-EO-01662 Category: Losartan Impurities Molecular Formula: C22H22ClN7O2 |
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Losartan Impurity 5Losartan Impurity 5 CAT No.: CS-EO-01341 Category: Losartan Impurities Molecular Formula: C22H21ClN6 |
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Losartan Impurity 6Losartan Impurity 6 CAT No.: CS-EO-01342 Category: Losartan Impurities Molecular Formula: C22H22ClN9 |
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Losartan Impurity 7Losartan Impurity 7 CAT No.: CS-T-88429 CAS Number: 358685-13-9 Category: Losartan Impurities |
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Losartan Impurity 8Losartan Impurity 8 CAT No.: CS-EO-01661 Category: Losartan Impurities Molecular Formula: C22H22ClN7O2 |
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Losartan isocyano ImpurityLosartan isocyano Impurity CAT No.: CS-O-43165 Category: Losartan Impurities Molecular Formula: C22H21ClN6 |
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Losartan N1-Trityl ImpurityLosartan N1-Trityl Impurity CAT No.: CS-O-15330 CAS Number: 124751-00-4 Category: Losartan Impurities Molecular Formula: C₄₁H₃₇ClN₆O |
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Losartan Potassium EP Impurity ALosartan Potassium EP Impurity A CAT No.: CS-T-09345 CAS Number: 79047-41-9 Category: Losartan Impurities |
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Losartan Potassium EP Impurity CLosartan Potassium EP Impurity C CAT No.: CS-T-31272 CAS Number: 860644-28-6 Category: Losartan Impurities Molecular Formula: C₂₂H₂₃ClKN₆O |
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Losartan Potassium EP Impurity ELosartan Potassium EP Impurity E CAT No.: CS-O-11951 CAS Number: 120568-11-8 Category: Losartan Impurities |
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Losartan Potassium EP Impurity HLosartan Potassium EP Impurity H CAT No.: CS-T-62580 CAS Number: 133909-99-6 Category: Losartan Impurities Molecular Formula: C₄₁H₃₇ClN₆O |
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Losartan Potassium EP Impurity JLosartan Potassium EP Impurity J CAT No.: CS-T-47310 CAS Number: 1006062-27-6 Category: Losartan Impurities Molecular Formula: C₂₄H₂₅ClN₆O₂ |
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Losartan Potassium EP Impurity KLosartan Potassium EP Impurity K CAT No.: CS-T-31265 CAS Number: 114798-36-6 Category: Losartan Impurities |
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Losartan Related Compound DLosartan Related Compound D CAT No.: CS-O-36027 CAS Number: 212316-86-4 Category: Losartan Impurities Molecular Formula: C44H43Cl2KN12O |
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Losartan Related Compound ELosartan Related Compound E CAT No.: CS-O-36028 CAS Number: 212316-88-6 Category: Losartan Impurities Molecular Formula: C44H43Cl2KN12O |
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Nitroso LosartanNitroso Losartan CAT No.: CS-O-35910 Category: Losartan Impurities Molecular Formula: C₂₂H₂₂ClN₇O₂ |
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N-Trityl Losartan CarboxaldehydeN-Trityl Losartan Carboxaldehyde CAT No.: CS-T-62581 CAS Number: 133910-00-6 Category: Losartan Impurities |
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N-Trityl Losartan Carboxylic AcidN-Trityl Losartan Carboxylic Acid CAT No.: CS-T-45965 CAS Number: 960231-60-1 Category: Losartan Impurities |
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N-Trityl Losartan IsomerN-Trityl Losartan Isomer CAT No.: CS-T-45961 CAS Number: 150098-04-7 Category: Losartan Impurities |
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"Losartan Imidazo[1,5-b]isoquinoline Impurity""Losartan Imidazo[1,5-b]isoquinoline Impurity" CAT No.: CS-T-57304 CAS Number: 165276-38-0 Category: Losartan Impurities |
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((2-Butyl-4-chloro-1-((2`-(1-nitroso-1H-tetrazol-5-yl)-[1,1`-biphenyl]-4-yl)methyl)-1H-imidazole-5-yl)methonol)((2-Butyl-4-chloro-1-((2`-(1-nitroso-1H-tetrazol-5-yl)-[1,1`-biphenyl]-4-yl)methyl)-1H-imidazole-5-yl)methonol) CAT No.: CS-O-40295 Category: Losartan Impurities Molecular Formula: C29H30ClN7O4 |
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(2-butyl-4-chloro-1-nitroso-1H-imidazole-5-yl)methanol(2-butyl-4-chloro-1-nitroso-1H-imidazole-5-yl)methanol CAT No.: CS-O-40296 Category: Losartan Impurities Molecular Formula: C8H12ClN3O2 |
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1-Acetyl-6-iodo-1H-indazole1-Acetyl-6-iodo-1H-indazole CAT No.: CS-O-40131 CAS Number: 850363-52-9 Category: Losartan Impurities Molecular Formula: C9H7IN2O |
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4-(4-Bromomethylphenyl)benzonitrile4-(4-Bromomethylphenyl)benzonitrile CAT No.: CS-O-40092 CAS Number: 50670-51-4 Category: Losartan Impurities Molecular Formula: C14H10BrN |
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5-Iodo-2-methylphenol5-Iodo-2-methylphenol CAT No.: CS-T-94041 CAS Number: 183803-06-7 Category: Losartan Impurities Molecular Formula: C7H7IO |
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Other Reference Standards of Losartan
PRODUCT
STRUCTURE
Deshydroxymethyl Losartan Trifluoroacetic Acid Salt
Deshydroxymethyl Losartan Trifluoroacetic Acid Salt
CAT No.: CS-T-52158
Category: Intermediates
CAS Number: 1215727-33-5
Losartan
Losartan
CAT No.: CS-O-10833
Category: API Standards
CAS Number: 114798-26-4
Molecular Formula: C₂₂H₂₃ClN₆O
Losartan acid D6 hydrochloride
Losartan acid D6 hydrochloride
CAT No.: CS-BU-00055
Category: Stable Isotopes
Losartan Acyl-β-D-glucuronide
Losartan Acyl-β-D-glucuronide
CAT No.: CS-O-05703
Category: Glucuronides
CAS Number: 1799830-02-6
Molecular Formula: C28H29ClN6O8
Losartan azide-d8
Losartan azide-d8
CAT No.: CS-O-40065
Category: Stable Isotopes
Molecular Formula: C22H14D8ClN9
Losartan carboxylic acid
Losartan carboxylic acid
CAT No.: CS-O-10324
Category: Metabolites
CAS Number: 124750-92-1
Molecular Formula: C₂₂H₂₁ClN₆O₂
Losartan Carboxylic acid D4
Losartan Carboxylic acid D4
CAT No.: CS-O-06731
Category: Stable Isotopes
CAS Number: 1246820-62-1
Molecular Formula: C₂₂H₁₇D₄ClN₆O₂
Losartan D2
Losartan D2
CAT No.: CS-O-02734
Category: Stable Isotopes
CAS Number: 1030936-22-1
Molecular Formula: C₂₂H₂₁D₂ClN₆O
Losartan D3
Losartan D3
CAT No.: CS-T-57300
Category: Stable Isotopes
CAS Number: 1030936-74-3
Losartan D4
Losartan D4
CAT No.: CS-O-02637
Category: Stable Isotopes
CAS Number: 1030937-27-9
Molecular Formula: C₂₂H₁₉D₄ClN₆O
Losartan for system suitability (Y0001076)
Losartan for system suitability (Y0001076)
CAT No.: CS-EG-02921
Category: EP Standards
Molecular Formula: C22H23ClN6O
Losartan impurity D (Y0001072)
Losartan impurity D (Y0001072)
CAT No.: CS-EG-02923
Category: EP Standards
CAS Number: 83857-96-9
Molecular Formula: C8H11ClN2O
Losartan N1-Glucuronide
Losartan N1-Glucuronide
CAT No.: CS-O-07894
Category: Glucuronides
CAS Number: 138584-34-6
Molecular Formula: C28H3ClN6O7
Losartan N2-glucuronide
Losartan N2-glucuronide
CAT No.: CS-P-05197
Category: Glucuronides
Losartan N2-β-D-glucuronide
Losartan N2-β-D-glucuronide
CAT No.: CS-O-30518
Category: Glucuronides
CAS Number: 138584-35-7
Molecular Formula: C28H31ClN6O7
Losartan potassium
Losartan potassium
CAT No.: CS-O-01767
Category: API Standards
CAS Number: 124750-99-8
Molecular Formula: C₂₂H₂₂ClKN₆O
Losartan Potassium (H1M331)
Losartan Potassium (H1M331)
CAT No.: CS-EB-01226
Category: USP Standards
CAS Number: 124750-99-8
Losartan potassium (Y0001062)
Losartan potassium (Y0001062)
CAT No.: CS-EG-02959
Category: EP Standards
CAS Number: 124750-99-8
Molecular Formula: C22H23ClKN6O
Losartan Potassium(Secondary Standards traceble to USP)
Losartan Potassium(Secondary Standards traceble to USP)
CAT No.: CS-ER-01221
Category: Secondary Standards
CAS Number: 124750-99-8
Losartan Related Compound A(Secondary Standards traceble to USP)
Losartan Related Compound A(Secondary Standards traceble to USP)
CAT No.: CS-ER-01222
Category: Secondary Standards
CAS Number: 83857-96-9
Losartan Related Compound B(Secondary Standards traceble to USP)
Losartan Related Compound B(Secondary Standards traceble to USP)
CAT No.: CS-ER-01223
Category: Secondary Standards
CAS Number: 1006062-27-6
Losartan Related Compound C(Secondary Standards traceble to USP)
Losartan Related Compound C(Secondary Standards traceble to USP)
CAT No.: CS-ER-01217
Category: Secondary Standards
CAS Number: 114798-36-6
Losartan Related Compound D (F01160)
Losartan Related Compound D (F01160)
CAT No.: CS-EB-01230
Category: USP Standards
CAS Number: 212316-86-4
Molecular Formula: C44H43Cl2KN12O
Losartan Related Compound D(Secondary Standards traceble to USP)
Losartan Related Compound D(Secondary Standards traceble to USP)
CAT No.: CS-ER-01218
Category: Secondary Standards
CAS Number: 212316-86-4
Losartan Related Compound E (F01170)
Losartan Related Compound E (F01170)
CAT No.: CS-EB-01231
Category: USP Standards
CAS Number: 212316-88-6
Molecular Formula: C44H43Cl2KN12O
Losartan Related Compound E(Secondary Standards traceble to USP)
Losartan Related Compound E(Secondary Standards traceble to USP)
CAT No.: CS-ER-01219
Category: Secondary Standards
CAS Number: 212316-88-6
Losartan Trityl Ether
Losartan Trityl Ether
CAT No.: CS-T-57303
Category: Intermediates
CAS Number: 1006062-28-7
Losartan-d3 Carboxylic Acid
Losartan-d3 Carboxylic Acid
CAT No.: CS-T-57301
Category: Stable Isotopes
CAS Number: 1189729-40-5
N-1-Ethoxyethyl Losartan Carboxaldehyde
N-1-Ethoxyethyl Losartan Carboxaldehyde
CAT No.: CS-T-22366
Category: Intermediates
CAS Number: 165276-40-4
N-1-Ethoxyethyl Losartan Carboxylic Acid
N-1-Ethoxyethyl Losartan Carboxylic Acid
CAT No.: CS-T-22367
Category: Intermediates
CAS Number: 165276-41-5
N-Trityl-deshydroxymethyl Losartan
N-Trityl-deshydroxymethyl Losartan
CAT No.: CS-T-88136
Category: Intermediates
CAS Number: 1797133-13-1
Trityl-Losartan D4
Trityl-Losartan D4
CAT No.: CS-Y-00101
Category: Stable Isotopes
CAS Number: 1309283-24-6
ω-1-Hydroxy Losartan
ω-1-Hydroxy Losartan
CAT No.: CS-T-56163
Category: Intermediates
CAS Number: 141675-57-2
2-Butyl-4-chloro-5-formylimidazole
2-Butyl-4-chloro-5-formylimidazole
CAT No.: CS-O-31530
Category: Intermediates
CAS Number: 83857-96-9
Molecular Formula: C₈H₁₁ClN₂O
5-Deshydroxymethyl-5-chloro Losartan
5-Deshydroxymethyl-5-chloro Losartan
CAT No.: CS-T-52157
Category: Intermediates
CAS Number: 1159977-26-0
ω-3-Hydroxy Losartan
ω-3-Hydroxy Losartan
CAT No.: CS-T-79242
Category: Intermediates
CAS Number: 141675-59-4
PRODUCT | STRUCTURE |
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Deshydroxymethyl Losartan Trifluoroacetic Acid SaltDeshydroxymethyl Losartan Trifluoroacetic Acid Salt CAT No.: CS-T-52158 Category: Intermediates CAS Number: 1215727-33-5 |
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LosartanLosartan CAT No.: CS-O-10833 Category: API Standards CAS Number: 114798-26-4 Molecular Formula: C₂₂H₂₃ClN₆O |
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Losartan acid D6 hydrochlorideLosartan acid D6 hydrochloride CAT No.: CS-BU-00055 Category: Stable Isotopes |
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Losartan Acyl-β-D-glucuronideLosartan Acyl-β-D-glucuronide CAT No.: CS-O-05703 Category: Glucuronides CAS Number: 1799830-02-6 Molecular Formula: C28H29ClN6O8 |
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Losartan azide-d8Losartan azide-d8 CAT No.: CS-O-40065 Category: Stable Isotopes Molecular Formula: C22H14D8ClN9 |
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Losartan carboxylic acidLosartan carboxylic acid CAT No.: CS-O-10324 Category: Metabolites CAS Number: 124750-92-1 Molecular Formula: C₂₂H₂₁ClN₆O₂ |
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Losartan Carboxylic acid D4Losartan Carboxylic acid D4 CAT No.: CS-O-06731 Category: Stable Isotopes CAS Number: 1246820-62-1 Molecular Formula: C₂₂H₁₇D₄ClN₆O₂ |
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Losartan D2Losartan D2 CAT No.: CS-O-02734 Category: Stable Isotopes CAS Number: 1030936-22-1 Molecular Formula: C₂₂H₂₁D₂ClN₆O |
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Losartan D3Losartan D3 CAT No.: CS-T-57300 Category: Stable Isotopes CAS Number: 1030936-74-3 |
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Losartan D4Losartan D4 CAT No.: CS-O-02637 Category: Stable Isotopes CAS Number: 1030937-27-9 Molecular Formula: C₂₂H₁₉D₄ClN₆O |
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Losartan for system suitability (Y0001076)Losartan for system suitability (Y0001076) CAT No.: CS-EG-02921 Category: EP Standards Molecular Formula: C22H23ClN6O |
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Losartan impurity D (Y0001072)Losartan impurity D (Y0001072) CAT No.: CS-EG-02923 Category: EP Standards CAS Number: 83857-96-9 Molecular Formula: C8H11ClN2O |
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Losartan N1-GlucuronideLosartan N1-Glucuronide CAT No.: CS-O-07894 Category: Glucuronides CAS Number: 138584-34-6 Molecular Formula: C28H3ClN6O7 |
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Losartan N2-glucuronideLosartan N2-glucuronide CAT No.: CS-P-05197 Category: Glucuronides |
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Losartan N2-β-D-glucuronideLosartan N2-β-D-glucuronide CAT No.: CS-O-30518 Category: Glucuronides CAS Number: 138584-35-7 Molecular Formula: C28H31ClN6O7 |
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Losartan potassiumLosartan potassium CAT No.: CS-O-01767 Category: API Standards CAS Number: 124750-99-8 Molecular Formula: C₂₂H₂₂ClKN₆O |
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Losartan Potassium (H1M331)Losartan Potassium (H1M331) CAT No.: CS-EB-01226 Category: USP Standards CAS Number: 124750-99-8 |
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Losartan potassium (Y0001062)Losartan potassium (Y0001062) CAT No.: CS-EG-02959 Category: EP Standards CAS Number: 124750-99-8 Molecular Formula: C22H23ClKN6O |
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Losartan Potassium(Secondary Standards traceble to USP)Losartan Potassium(Secondary Standards traceble to USP) CAT No.: CS-ER-01221 Category: Secondary Standards CAS Number: 124750-99-8 |
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Losartan Related Compound A(Secondary Standards traceble to USP)Losartan Related Compound A(Secondary Standards traceble to USP) CAT No.: CS-ER-01222 Category: Secondary Standards CAS Number: 83857-96-9 |
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Losartan Related Compound B(Secondary Standards traceble to USP)Losartan Related Compound B(Secondary Standards traceble to USP) CAT No.: CS-ER-01223 Category: Secondary Standards CAS Number: 1006062-27-6 |
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Losartan Related Compound C(Secondary Standards traceble to USP)Losartan Related Compound C(Secondary Standards traceble to USP) CAT No.: CS-ER-01217 Category: Secondary Standards CAS Number: 114798-36-6 |
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Losartan Related Compound D (F01160)Losartan Related Compound D (F01160) CAT No.: CS-EB-01230 Category: USP Standards CAS Number: 212316-86-4 Molecular Formula: C44H43Cl2KN12O |
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Losartan Related Compound D(Secondary Standards traceble to USP)Losartan Related Compound D(Secondary Standards traceble to USP) CAT No.: CS-ER-01218 Category: Secondary Standards CAS Number: 212316-86-4 |
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Losartan Related Compound E (F01170)Losartan Related Compound E (F01170) CAT No.: CS-EB-01231 Category: USP Standards CAS Number: 212316-88-6 Molecular Formula: C44H43Cl2KN12O |
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Losartan Related Compound E(Secondary Standards traceble to USP)Losartan Related Compound E(Secondary Standards traceble to USP) CAT No.: CS-ER-01219 Category: Secondary Standards CAS Number: 212316-88-6 |
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Losartan Trityl EtherLosartan Trityl Ether CAT No.: CS-T-57303 Category: Intermediates CAS Number: 1006062-28-7 |
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Losartan-d3 Carboxylic AcidLosartan-d3 Carboxylic Acid CAT No.: CS-T-57301 Category: Stable Isotopes CAS Number: 1189729-40-5 |
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N-1-Ethoxyethyl Losartan CarboxaldehydeN-1-Ethoxyethyl Losartan Carboxaldehyde CAT No.: CS-T-22366 Category: Intermediates CAS Number: 165276-40-4 |
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N-1-Ethoxyethyl Losartan Carboxylic AcidN-1-Ethoxyethyl Losartan Carboxylic Acid CAT No.: CS-T-22367 Category: Intermediates CAS Number: 165276-41-5 |
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N-Trityl-deshydroxymethyl LosartanN-Trityl-deshydroxymethyl Losartan CAT No.: CS-T-88136 Category: Intermediates CAS Number: 1797133-13-1 |
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Trityl-Losartan D4Trityl-Losartan D4 CAT No.: CS-Y-00101 Category: Stable Isotopes CAS Number: 1309283-24-6 |
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ω-1-Hydroxy Losartanω-1-Hydroxy Losartan CAT No.: CS-T-56163 Category: Intermediates CAS Number: 141675-57-2 |
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2-Butyl-4-chloro-5-formylimidazole2-Butyl-4-chloro-5-formylimidazole CAT No.: CS-O-31530 Category: Intermediates CAS Number: 83857-96-9 Molecular Formula: C₈H₁₁ClN₂O |
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5-Deshydroxymethyl-5-chloro Losartan5-Deshydroxymethyl-5-chloro Losartan CAT No.: CS-T-52157 Category: Intermediates CAS Number: 1159977-26-0 |
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ω-3-Hydroxy Losartanω-3-Hydroxy Losartan CAT No.: CS-T-79242 Category: Intermediates CAS Number: 141675-59-4 |
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