Venetoclax Impurities

Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or acute myeloid leukemia (AML).

The most common side effects are low levels of neutrophils (a type of white blood cell), diarrhea, nausea, anemia (low red blood cell counts), nose and throat infection and tiredness.

Venetoclax attaches to a protein called Bcl-2. This protein is present in high amounts in CLL cancer cells, where it helps the cells survive for longer in the body and makes them resistant to cancer medicines. By attaching to Bcl-2 and blocking its actions, venetoclax causes the death of cancer cells and thereby slows down progression of the disease.




List of Impurities of Venetoclax  Download Catalog


CAT No. PRODUCT CATEGORY IMAGE
CS-O-33292
Deschloro Venetoclax
Venetoclax Impurities Venetoclax Impurities
CS-O-36758
methyl 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
Venetoclax Impurities Venetoclax Impurities
CS-T-93808
methyl 2,4-bis(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
Venetoclax Impurities Venetoclax Impurities
CS-O-36796
methyl 3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonate
Venetoclax Impurities Venetoclax Impurities
CS-O-36795
methyl 4-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-2-fluorobenzoate
Venetoclax Impurities Venetoclax Impurities
CS-O-36757
methyl 4-fluoro-2-{5-[5-fluoro-2-(methoxycarbonyl)phenoxy]-1H-pyrrolo[2,3-b]pyridin-1-yl}benzoate
Venetoclax Impurities Venetoclax Impurities
CS-O-36766
Venetoclax Acyl urea impurity 2
Venetoclax Impurities Venetoclax Impurities
CS-O-36765
Venetoclax Acyl urea impurity 1
Venetoclax Impurities Venetoclax Impurities
CS-O-36763
Venetoclax API chloro coupled impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36764
Venetoclax API N-coupled impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36762
Venetoclax desfluoro impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-44362
Venetoclax fluoro impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-33811
Venetoclax Hydroxyl impurity(Venetoclax Impurity M3)
Venetoclax Impurities Venetoclax Impurities
CS-EO-00673
Venetoclax Imp 8
Venetoclax Impurities Venetoclax Impurities
CS-EO-00674
Venetoclax Imp 9
Venetoclax Impurities Venetoclax Impurities
CS-O-36798
Venetoclax Impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36800
Venetoclax Impurity - 1
Venetoclax Impurities Venetoclax Impurities
CS-O-16740
Venetoclax Impurity 1
Venetoclax Impurities Venetoclax Impurities
CS-EO-00675
Venetoclax Impurity 11
Venetoclax Impurities Venetoclax Impurities
CS-EO-00676
Venetoclax Impurity 12
Venetoclax Impurities Venetoclax Impurities
CS-EO-00677
Venetoclax Impurity 13
Venetoclax Impurities Venetoclax Impurities
CS-O-16741
Venetoclax Impurity 2
Venetoclax Impurities Venetoclax Impurities
CS-EO-00994
Venetoclax Impurity 28
Venetoclax Impurities Venetoclax Impurities
CS-O-16742
Venetoclax Impurity 3
Venetoclax Impurities Venetoclax Impurities
CS-O-43354
Venetoclax Impurity 31
Venetoclax Impurities Venetoclax Impurities
CS-EO-02208
Venetoclax Impurity 34
Venetoclax Impurities Venetoclax Impurities
CS-EO-02214
Venetoclax Impurity 35
Venetoclax Impurities Venetoclax Impurities
CS-O-16743
Venetoclax Impurity 4
Venetoclax Impurities Venetoclax Impurities
CS-O-16744
Venetoclax Impurity 5
Venetoclax Impurities Venetoclax Impurities
CS-O-16745
Venetoclax Impurity 6
Venetoclax Impurities Venetoclax Impurities
CS-O-16746
Venetoclax Impurity 7
Venetoclax Impurities Venetoclax Impurities
CS-O-16747
Venetoclax Impurity 8
Venetoclax Impurities Venetoclax Impurities
CS-O-16748
Venetoclax Impurity 9
Venetoclax Impurities Venetoclax Impurities
CS-O-36425
Venetoclax KSM-II(Des chloro)
Venetoclax Impurities Venetoclax Impurities
CS-O-44363
Venetoclax N-Des tetrahydro-2H-pyran-4-ylmethyl
Venetoclax Impurities Venetoclax Impurities
CS-O-33812
Venetoclax N-oxide
Venetoclax Impurities Venetoclax Impurities
CS-EO-02213
Venetoclax Oxalic Acid
Venetoclax Impurities Venetoclax Impurities
CS-O-36759
Venetoclax Stage-I chloro coupled acid impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36761
Venetoclax Stage-I N-coupled acid impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36760
Venetoclax Stage-I N-hydroxy acid impurity
Venetoclax Impurities Venetoclax Impurities
CS-O-36813
1-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)ph
Venetoclax Impurities Venetoclax Impurities
CS-O-36801
2-((1H-pyrrolo[2,3-b]pyridin-5-yl)methyl)-4-(5-(2-carboxy-5-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetr
Venetoclax Impurities Venetoclax Impurities
CS-O-36799
2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphen
Venetoclax Impurities Venetoclax Impurities
CS-O-36794
2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoic acid
Venetoclax Impurities Venetoclax Impurities
CS-O-36797
3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonic acid
Venetoclax Impurities Venetoclax Impurities
CS-O-36793
4'-chloro-3,3-dimethyl-6-(piperazin-1-ylmethyl)-2,3,4,5-tetrahydro-[1,1'-biphenyl]-2-ol
Venetoclax Impurities Venetoclax Impurities

Other Reference Standards of Venetoclax


What is Venetoclax Impurities?

  • Venetoclax Impurities are the components of Venetoclax which are not the defined active substance of Venetoclax
  • They are unwanted chemicals that remain with active pharmaceutical ingredients of Venetoclax
  • Some of Venetoclax Impurities can be used for evaluating data that establishes quality
  • They are also used for stability and biological safety of pharmaceutical products
  • Venetoclax Impurities can also be used for ANDA / DMF filling and genotoxicity studies.


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