Arterolane is an antimalarial drug that is used to treat malaria. During the manufacturing process of arterolane, impurities can be formed. These impurities can affect the purity and quality of the final product. Therefore, it is important to identify and control the impurities to ensure the safety and efficacy of arterolane. Various analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) are used to detect and quantify the impurities in arterolane.