Diosmin is a flavonoid commonly used in pharmaceuticals and dietary supplements for its anti-inflammatory and venotonic properties. However, like any other chemical compound, Diosmin may contain impurities that can affect its quality, safety, and efficacy. These impurities can be residual solvents, heavy metals, organic and inorganic compounds, and other contaminants that may arise from the manufacturing process or storage conditions. Therefore, it is essential to control and monitor Diosmin impurities to ensure that the