Neamine is an aminoglycoside antibiotic that is used to treat bacterial infections. During the manufacturing process, impurities may be formed that can affect the quality and safety of the drug. Neamine impurities can include related compounds, degradation products, and residual solvents. It is important to monitor and control these impurities to ensure the efficacy and safety of the drug. Analytical methods such as HPLC and LC-MS are commonly used for this purpose.