Displaying 2 results of Nicardipine Hydrochloride Impurities Nicardipine Hydrochloride is a calcium channel blocker used in treating high blood pressure and angina. However, the drug may contain impurities, which are substances that are not intended to be in the drug but may be present due to the manufacturing process or storage conditions. These impurities may affect the safety and efficacy of the drug and must be monitored and controlled. Some of the impurities associated with Nicardipine Hydrochloride include N-Desmethylnicardipine, Nicardipine N-oxide, and Nicardipine dimer.