(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 HCl

(±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 HCl, also known as d5-amphetamine, is a deuterated form of amphetamine. It is a psychoactive drug that stimulates the central nervous system, producing effects such as increased alertness, euphoria, and decreased appetite. It is commonly used as a prescription medication for attention deficit hyperactivity disorder (ADHD) and narcolepsy. The deuterated form of amphetamine has been used in medical research to study the pharmacokinetics and metabolism of amphetamine in the body. Deuterium is a stable isotope of hydrogen, and its incorporation into the molecule of amphetamine allows for the tracking of the drug's metabolic fate in the body. This information can be used to optimize dosing regimens and improve the safety and efficacy of amphetamine-based medications. Chemically, (±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 HCl has a molecular weight of 183.71 g/mol and a molecular formula of C9H14D5ClN. It is a white to off-white crystalline powder that is soluble in water. The deuterium atoms in the molecule are located at the benzylic and alpha-carbon positions, resulting in a fivefold increase in the mass of the molecule compared to regular amphetamine. The HCl salt form of d5-amphetamine is commonly used for pharmaceutical purposes due to its stability and solubility.