(2S,3S)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

(2S,3S)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol is a synthetic compound that belongs to the class of triazole antifungal agents. It is commonly used in the treatment of fungal infections caused by Candida species, including Candida albicans, which is one of the most common causes of fungal infections in humans. The chemical structure of (2S,3S)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol contains a triazole ring, which is a five-membered heterocyclic ring containing three carbon atoms and two nitrogen atoms. This ring acts as a potent inhibitor of fungal cytochrome P450 enzymes, which are essential for the synthesis of ergosterol, a vital component of fungal cell membranes. By inhibiting the synthesis of ergosterol, (2S,3S)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol disrupts the integrity of fungal cell membranes, leading to cell death and ultimately eradicating the fungal infection. The compound is available in both oral and intravenous formulations and is administered under the supervision of a healthcare professional. It is generally well-tolerated with minimal side effects, although some patients may experience gastrointestinal disturbances, headaches, or skin rashes. Overall, (2S,3S)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol is an effective and safe antifungal agent that has revolutionized the treatment of fungal infections.