(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone

(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone is a chemical compound that belongs to the class of azetidinones. The compound has a molecular formula of C21H35NO4Si and a molecular weight of 409.6 g/mol. This compound is used in the pharmaceutical industry for the synthesis of various drugs and drug candidates. The compound is characterized by the presence of a t-Boc (tert-butoxycarbonyl) protecting group on the amine nitrogen, which provides stability to the molecule during chemical reactions. The triethylsilyl group attached to the oxygen atom enhances the compound's lipophilicity, making it more soluble in organic solvents. The phenyl group attached to the azetidinone ring provides additional stability to the molecule. (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone is commonly used in the synthesis of β-lactam antibiotics, which are widely used in the treatment of bacterial infections. It is also used in the synthesis of other drugs such as antifungal agents, antiviral agents, and anticancer drugs. The compound's unique structure and properties make it an important intermediate in the synthesis of various pharmaceuticals. In conclusion, (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone is a versatile and widely used intermediate in the synthesis of various drugs and drug candidates. Its stability, solubility, and lipophilicity make it an important compound in the pharmaceutical industry.