11,17,21-Trihydroxy-pregn-5-ene-3,20-dione-d4 3,20-Diethylene Ketal

11,17,21-Trihydroxy-pregn-5-ene-3,20-dione-d4 3,20-Diethylene Ketal, also known as cortisone-d4, is a synthetic form of the hormone cortisol. It is used in medical research and diagnostics as a labeled compound for studying the metabolism and functions of cortisol in the body. The "d4" in the name indicates that four of the hydrogen atoms in the molecule have been replaced with deuterium, a heavier isotope of hydrogen. This labeling makes it easier to track the movement of cortisol in the body and distinguish it from naturally occurring cortisol. Cortisol is a steroid hormone produced by the adrenal gland in response to stress. It plays a role in regulating many physiological processes, including metabolism, immune response, and the body's stress response. Cortisone-d4 is used in research to study the effects of cortisol on these processes and to develop new diagnostic tests for cortisol-related disorders. In terms of its chemical properties, cortisone-d4 has the molecular formula C23H28D4O6 and a molecular weight of 412.53 g/mol. It is a white crystalline powder that is soluble in ethanol and methanol but insoluble in water. It has a melting point of 235-237°C and a purity of at least 98%. Cortisone-d4 should be handled with care, as it can be harmful if ingested, inhaled, or absorbed through the skin.