[13C6]-Tofogliflozin

[13C6]-Tofogliflozin is a stable isotope-labeled version of the active pharmaceutical ingredient tofogliflozin. Tofogliflozin belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors, which are used in the treatment of type 2 diabetes mellitus. SGLT2 inhibitors work by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion and lower blood glucose levels. [13C6]-Tofogliflozin can be used as a tracer in pharmacokinetic and metabolic studies. The stable isotope labeling allows for the tracking of the drug in the body and the determination of its fate and metabolism. This information can be useful in drug development, as it can aid in optimizing dosing and reducing potential adverse effects. The chemical formula of [13C6]-Tofogliflozin is C21H20C6NO7S2, and its molecular weight is 510.6 g/mol. The stable isotope labeling involves replacing six carbon atoms in the molecule with their heavier counterparts, carbon-13. This labeling does not affect the pharmacological activity of the drug and is safe for human use. In conclusion, [13C6]-Tofogliflozin is a useful tool in pharmacokinetic and metabolic studies of tofogliflozin. Its stable isotope labeling allows for the tracking of the drug in the body and the determination of its fate and metabolism. This information can aid in drug development and optimization.