(2R,3S,11bS)-Dihydrotetrabenazine-d6

Product Name (2R,3S,11bS)-Dihydrotetrabenazine-d6
Alternate Names Tetrabenazine Stable Isotopes, Stable Isotopes of Tetrabenazine
CAT No. CS-T-89760
CAS No. 1583277-33-1
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Tetrabenazine
Smileys O[C@H]1[C@@H](CC(C)C)CN2CCC3=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C3[C@]2([H])C1
Canonical Smiles CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1O)OC)OC
InchIKey WEQLWGNDNRARGE-RXXFDNCFSA-N
Inchl InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17+/m0/s1/i3D3,4D3
IUPAC (2R,3S,11bS)-3-(2-methylpropyl)-9,10-bis(trideuteriomethoxy)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
Controlled No
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(2R,3S,11bS)-Dihydrotetrabenazine-d6 is a deuterated form of the drug tetrabenazine, which is commonly used to treat movement disorders such as Huntington's disease, tardive dyskinesia, and Tourette syndrome. The drug works by reducing the amount of dopamine in the brain, which helps to control involuntary movements. Deuterated compounds are used in pharmaceutical research to help identify the metabolic pathways of drugs and their potential interactions with other compounds. The use of deuterium can also help to increase the stability of drugs and reduce toxicity. The addition of six deuterium atoms to (2R,3S,11bS)-Dihydrotetrabenazine provides a useful tool for researchers to study the pharmacokinetics and metabolic pathways of tetrabenazine. This compound can be used as a reference standard in studies involving tetrabenazine and its metabolites, as well as in the development of new drugs that target the same pathways. In terms of chemical information, (2R,3S,11bS)-Dihydrotetrabenazine-d6 has a molecular formula of C19H20D6N2O and a molecular weight of 308.46 g/mol. It is a white solid that is soluble in organic solvents such as methanol and dimethyl sulfoxide. The compound has a melting point of 170-172°C and a boiling point of 446-453°C. It should be stored in a cool, dry place away from light and air.

Related Compounds

Deutetrabenazine | Deutetrabenazine metabolite M1 | Related trans tetrabenazine D6 | Didehydro tetrabenazine-d6 | Cis-2,3 dihydrotetrabenazine 13C2 D6 | cis-2,3 dihydro tetrabenazine-D6 | Tetrabenazine-D7 | Deutetrabenazine metabolite M4 | alpha-Hydroxy Tetrabenazine-d7 | Trans (2,3)-Dihydrotetrabenazine 13C2 D6 | Dihydrotetrabenazine-D6 | Tetrabenazine D6 | Tetrabenazine D3 (Mixture of 9&10 Methoxy D3) |

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