(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5

(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5 is a complex organic compound with a molecular formula of C15H5D5NO7. It is a deuterated derivative of the natural product known as swainsonine. Swainsonine is a potent inhibitor of lysosomal alpha-mannosidase, and it has been shown to have antitumor and antiviral properties. In addition to its potential therapeutic applications, swainsonine is also of interest to researchers studying glycoprotein processing and protein folding. The deuterated derivative of swainsonine, (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5, is useful in studies that require a labeled compound for tracing and quantification purposes. It is also useful in drug metabolism and pharmacokinetic studies, as it can provide information on the absorption, distribution, metabolism, and excretion of swainsonine and its derivatives. In terms of its chemical properties, (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5 is a white to off-white solid that is soluble in water and organic solvents. It has a melting point of approximately 200-210°C and a boiling point of approximately 570°C. Its structure contains a pyran ring, an indolizine ring, and a trione moiety. Overall, (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5 is a valuable compound for researchers studying glycoprotein processing, protein folding, and drug metabolism. Its labeled structure allows for precise quantification and tracing, making it an important tool in various fields of research.