6-amino-3-methyl-5-nitroso-1H-pyrimidine-2,4-dione

6-amino-3-methyl-5-nitroso-1H-pyrimidine-2,4-dione, also known as AMNPD, is a chemical compound that is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs. AMNPD is a yellow crystalline powder that is soluble in water and has a melting point of 230-234°C. It is a nitroso derivative of uracil and contains an amino group and a methyl group at positions 6 and 3 respectively. The compound has an acidic character and can form salts with bases. AMNPD is extensively used in the synthesis of antiviral, antitumor, and antimicrobial drugs. It acts as a potent inhibitor of DNA polymerase and is used as a prodrug for the treatment of herpes simplex virus and hepatitis B virus infections. AMNPD also exhibits antitumor activity and has been shown to inhibit the growth of various cancer cell lines. In conclusion, AMNPD is a versatile chemical compound that finds extensive use as a building block for the synthesis of various drugs. Its unique chemical properties make it a valuable tool for the development of new therapeutics, particularly in the field of antiviral and anticancer drug discovery.