[Ring-13C6]-Mitotan

[Ring-13C6]-Mitotan is a stable isotopically labeled form of Mitotan, also known as o,p’-DDD or Lysodren. Mitotan is a chemotherapy drug used to treat adrenal cancers, specifically in cases where tumors cannot be surgically removed. It works by targeting and destroying the cells in the adrenal glands that produce excess hormones. [Ring-13C6]-Mitotan is used in clinical research studies to determine the pharmacokinetics and metabolism of Mitotan in the body. It is also used to investigate the drug’s efficacy and potential toxicity in patients with adrenal cancer. The chemical formula of [Ring-13C6]-Mitotan is C14H10Cl4O2 and its molecular weight is 394.04 g/mol. The 13C6-labeled ring in the molecule allows for precise tracking and identification of the drug in biological samples using mass spectrometry techniques. The recommended dosage of Mitotan varies depending on the patient’s weight and the severity of their condition. Common side effects of Mitotan treatment include nausea, vomiting, fatigue, and loss of appetite. Patients taking Mitotan are also advised to avoid alcohol and grapefruit juice, as they can interact with the drug and increase its toxicity. Overall, [Ring-13C6]-Mitotan is a valuable tool in research and clinical settings for investigating the pharmacokinetics and efficacy of Mitotan in treating adrenal cancer.