1,3-Bis(2-chloroethyl-d4)-1-nitrosourea

1,3-Bis(2-chloroethyl-d4)-1-nitrosourea (BCNU-d4) is a chemical compound that is used in chemotherapy to treat certain types of brain cancer, such as gliomas and medulloblastomas. It is a nitrosourea derivative and works by damaging the DNA in cancer cells, ultimately leading to their death. BCNU-d4 is administered intravenously and is often used in combination with other chemotherapy drugs. It is a potent cytotoxic agent and can cause a range of side effects, including nausea, vomiting, hair loss, and decreased blood cell counts. Patients receiving BCNU-d4 are closely monitored for these and other potential side effects. Chemically, BCNU-d4 is a stable, water-soluble compound with a molecular weight of 217.6 g/mol. It is a clear, colorless liquid that is highly reactive due to the presence of the nitrosourea and chloroethyl groups. BCNU-d4 is highly toxic and must be handled with care by trained professionals. Overall, 1,3-Bis(2-chloroethyl-d4)-1-nitrosourea is a powerful chemotherapy drug used in the treatment of brain cancer. While it can cause significant side effects, it is an important tool in the fight against this devastating disease.