1-Amino-3,5-dimethyl-d6-adamantane-2,2,7,8,8,9,9-d7 HCl

1-Amino-3,5-dimethyl-d6-adamantane-2,2,7,8,8,9,9-d7 HCl is a deuterated form of a compound used in medicinal chemistry research. It is primarily used as a pharmacological tool to study the effects of the parent compound, 1-Amino-3,5-dimethyladamantane (also known as Memantine), on the central nervous system. Memantine is a non-competitive NMDA receptor antagonist that has been approved by the US FDA for the treatment of moderate to severe Alzheimer's disease. It works by binding to the NMDA receptor and blocking the activity of glutamate, an excitatory neurotransmitter. This helps to prevent neuronal damage and improve cognitive function in patients with Alzheimer's disease. The deuterated form of this compound, 1-Amino-3,5-dimethyl-d6-adamantane-2,2,7,8,8,9,9-d7 HCl, is used in research to study the pharmacokinetics and metabolic pathways of Memantine in vivo. Deuterated compounds have a slightly higher molecular weight than their non-deuterated counterparts, which can affect their absorption, distribution, metabolism, and excretion in the body. By using deuterated compounds, researchers can gain a better understanding of how a drug is processed by the body and how it interacts with its target receptors. Overall, 1-Amino-3,5-dimethyl-d6-adamantane-2,2,7,8,8,9,9-d7 HCl is an important tool for researchers studying the pharmacology of Memantine and its potential applications in treating neurological disorders.