1-Nitroso-3,5-dimethyladamantane

1-Nitroso-3,5-dimethyladamantane, also known as NDMA, is a chemical compound that belongs to the group of adamantane derivatives. It is a pale yellow solid crystalline powder with a molecular formula of C12H17NO and a molecular weight of 191.28 g/mol. NDMA is highly soluble in organic solvents such as ethanol, acetone, and chloroform, but poorly soluble in water. NDMA has been used in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as a reagent in organic chemistry for the formation of nitrosoalkanes. NDMA has been studied for its potential applications in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. However, NDMA is also a toxic compound that poses significant health risks to humans. It is classified as a probable human carcinogen by the International Agency for Research on Cancer (IARC). NDMA exposure can occur through inhalation, ingestion, or skin contact. It is known to cause liver damage, respiratory distress, and other adverse health effects. NDMA has been identified as a contaminant in several products, including food, water, and medication. Exposure to NDMA can occur through the consumption of contaminated food or water, or through the use of contaminated medication. As a result, regulatory agencies such as the US Food and Drug Administration (FDA) have set limits on the acceptable levels of NDMA in various products.