2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2

2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2 is a labeled form of the organic compound 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine, also known as Mebendazole. It is a broad-spectrum anthelmintic drug used to treat parasitic infections, including roundworms, hookworms, whipworms, and pinworms, in both humans and animals. Mebendazole works by inhibiting the microtubule function and preventing the helminths from absorbing glucose, leading to their eventual death. The labeled form of Mebendazole, 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2, is used in research and studies to track the metabolic pathway and pharmacokinetics of Mebendazole in the body. It is also used in pharmacokinetic studies to determine the bioavailability, distribution, metabolism, and excretion of Mebendazole in the body. The chemical formula of 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2 is C8H5N5O3^13C2, and its molecular weight is 230.18 g/mol. It is a crystalline powder that is stable under normal conditions. The compound is soluble in water, DMSO, and ethanol, and has a melting point of 288-291°C. In conclusion, 2,6-Diamino-4-hydroxy-5-nitrosopyrimidine-13C2 is an important labeled form of Mebendazole used in pharmacokinetic studies and research. It is a potent anthelmintic drug used to treat parasitic infections in humans and animals and works by inhibiting the microtubule function and preventing the absorption of glucose by helminths. Its chemical properties make it suitable for use in various research applications related to the bioavailability, distribution, metabolism, and excretion of Mebendazole in the body.