3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine

3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine, also known as NIPAH, is a chemical compound primarily used as a biochemical research tool. It is a potent inhibitor of nitric oxide synthase (NOS), an enzyme that catalyzes the production of nitric oxide (NO) from L-arginine. NIPAH can inhibit both the constitutive and inducible forms of NOS, making it useful in studying the role of NO in various physiological processes. In addition to its research applications, NIPAH has also shown potential therapeutic benefits. Studies have suggested that NIPAH may be useful in treating conditions such as sepsis, inflammation, and neurodegenerative diseases. Chemically, NIPAH is a hydrazine derivative with a nitroso group and a hydroxyl group attached to the same carbon atom. It has a molecular formula of C6H15N3O2 and a molecular weight of 161.2 g/mol. NIPAH is a white to off-white powder that is soluble in water and ethanol but insoluble in organic solvents. NIPAH should be handled with care as it is a potentially hazardous compound. It is recommended that it be stored in a cool, dry place away from heat sources and oxidizing agents. Protective equipment, such as gloves and goggles, should be worn when handling NIPAH to prevent skin and eye irritation.