3-(Methylnitrosamino)propionitrile
| Product Name | 3-(Methylnitrosamino)propionitrile |
|---|---|
| CAT No. | CS-T-34669 |
| CAS No. | 60153-49-3 |
| Category | Intermediates |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Canonical Smiles | CN(CCC#N)N=O |
| InchIKey | HZDLDFBKYBGNHG-UHFFFAOYSA-N |
| Inchl | InChI=1S/C4H7N3O/c1-7(6-8)4-2-3-5/h2,4H2,1H3 |
| IUPAC | N-(2-cyanoethyl)-N-methylnitrous amide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3-(Methylnitrosamino)propionitrile (NNK) is a potent carcinogen, which is present in tobacco smoke, and has been identified as a major cause of lung cancer in smokers. NNK is a nitrosamine, which is formed during the curing process of tobacco leaves. The chemical formula for NNK is C10H14N2O2, and it has a molecular weight of 202.23 g/mol. NNK is a colorless to light yellow liquid, which is soluble in water, ethanol, and methanol.
NNK is metabolized in the liver by the cytochrome P450 enzyme system to form reactive intermediates, which can bind to DNA and cause mutations. The DNA adducts formed by NNK are highly mutagenic and can lead to the formation of tumors. NNK is also known to cause oxidative stress, which can damage cell membranes and proteins, leading to cell death and inflammation.
Despite the known health risks associated with NNK, it is still used in research to study the mechanisms of lung cancer and to develop new treatments for the disease. NNK is also used in animal studies to test the efficacy of drugs designed to prevent lung cancer. However, the use of NNK in research is strictly regulated due to its toxicity and carcinogenicity.
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