3-Deoxyglucosone-13C

3-Deoxyglucosone-13C is a stable isotope labeled compound that is commonly used in biochemical research and medical studies. It is a derivative of 3-deoxyglucosone, which is a reactive intermediate involved in the Maillard reaction in foods and in the formation of advanced glycation end-products (AGEs) in the body. AGEs are known to contribute to various diseases such as diabetes, atherosclerosis, and Alzheimer’s disease. The stable isotope labeling of 3-deoxyglucosone-13C allows for the measurement of metabolic turnover rates and pathways in vivo, as well as the identification and quantification of 3-deoxyglucosone in biological samples using mass spectrometry. This is particularly useful in studying the formation and accumulation of AGEs in various tissues and organs, as well as their impact on cellular functions and disease progression. In addition to its research applications, 3-deoxyglucosone-13C is also used in the development and testing of drugs and therapeutic interventions for diseases associated with AGEs. Its chemical structure and properties make it an important tool in the discovery of new drugs and treatments that can prevent or reduce the formation of AGEs and their harmful effects. Overall, 3-deoxyglucosone-13C is a valuable compound in biochemical research and medical studies that offers insights into the formation and impact of AGEs in the body, as well as potential avenues for disease prevention and treatment.