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3-Hydroxy-N-nitrosopiperidine, also known as HONP, is a nitrosamine compound used in various fields such as pharmaceuticals, agriculture, and food processing. It is typically used as a synthetic intermediate in the production of other compounds, such as the anti-cancer drug, temozolomide.
Chemically, HONP is a colorless to light yellow crystalline solid that is soluble in water and organic solvents. It has a molecular formula of C6H11N3O2 and a molecular weight of 157.17 g/mol. HONP is known to be highly unstable and can easily decompose into various degradation products, including N-nitrosopiperidine (NPIP) and 3-hydroxypiperidine.
In terms of its usage, HONP is primarily used as a reagent in the synthesis of other compounds. It is also used as a research tool to investigate the carcinogenic potential of nitrosamines. However, due to its potential carcinogenicity, HONP is highly regulated by various government agencies, including the US Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA).
Overall, while 3-Hydroxy-N-nitrosopiperidine has various applications in the chemical industry, its potential health hazards and instability make it a highly regulated and controlled substance. Proper safety measures and handling procedures should be followed when working with this compound.
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