4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4

Product Name 4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4
CAT No. CS-T-98774
CAS No. Not Available
Category Stable Isotopes
Stock Enquire
Mol. Wt. 227.25 g/mol
Mol. For. C10H9D4N3O3
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Controlled No
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4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4 is a stable isotope-labeled internal standard used for high-performance liquid chromatography (HPLC) analysis and mass spectrometry (MS) analysis of 4-(Methylnitrosamino)-4-(3-pyridyl)butyric acid (NNAL), a potent carcinogen and biomarker for tobacco smoke exposure. NNAL is formed in the body from the metabolism of the tobacco-specific nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which is found in cigarette smoke. NNAL is also present in urine and can be used to assess the level of tobacco smoke exposure. The deuterium-labeled 4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4 is added to the urine sample as an internal standard to accurately quantify the amount of NNAL present in the sample. This helps to ensure the accuracy and precision of the results. 4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4 has a molecular formula of C11H8D4N3O3 and a molecular weight of 256.29 g/mol. It is a clear, colorless liquid that is stable under normal conditions. Overall, the use of 4-(Methylnitrosamino)-4-(3-pyridyl)butyric Acid-d4 is critical for accurate and reliable quantification of NNAL in biological samples, allowing for better assessment of tobacco smoke exposure and its associated health risks.

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